פיצול מכוון של קולטן תא mhc

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专利权人:

Sangamo Therapeutics Inc.

发明人:

申请号：

IL25993518

公开号：

IL259935D0

申请日:

2018.06.11

申请国别(地区):

IL

年份:

2018

代理人:

摘要：

Disclosed herein are methods and compositions for inactivating MEW genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain in conditions able to preserve cell viability. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/