Xiao Min Schebye,Mark J. Selby,Michelle Minhua Han,Christine Bee,Andy X. Deng,Anan Chuntharapai,Brigitte Devaux,Huiming Li,Paul O. Sheppard,Alan J. Korman,Daniel F. Ardourel,Ekaterina Deyanova,Richard
申请号：
US15649380
公开号：
US10077306B2
申请日:
2017.07.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
