The method of new biomarker object and treating cancer

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专利权人:

アストラゼネカ・アクチエボラーグ

发明人:

アルバロ・アビバル・バルデラス,フランシスコ・ウンベルト・クルサレギ,ケビン・ハドソン,ロバート・ケネス・マキューアン

申请号：

JP2018513288

公开号：

JP2018531223A6

申请日:

2016.09.16

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The paths treatment PI3K of the relevant pathological condition of biomarker, such as cancer, and using the paths upstream component PI3K such as PI3K- α AKT inhibitor or the inhibitor of inhibitor, be described. Especially, describe the method that biomarker patient selects treatment malignant tumour, and treatment, diagnostic kit and its method of detection, wherein cancer possesses the PI3K approach (such as PIK3CA genes and/or AKT genes) and wild type MAP3K1 genes and MAP2K4 genes of a mutation upstream component, is more likely to successfully respond the upstream component PI3K approach of processing and inhibitor.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/