LYNCH KEVIN R.,MACDONALD TIMOTHY L.,HEASLEY BRIAN H.
申请号：
US20050579658
公开号：
US7820703(B2)
申请日:
2005.05.06
申请国别(地区):
美国
年份:
2010
代理人:
摘要：
The present invention is directed to compositions comprising lysophosphatidic acid analogs and methods of using such analogs as agonist or antagonists of LPA receptor activity. In addition the invention is directed to LPA receptor agonists that vary in the degree of selectivity at individual LPA receptors (i.e. LPA1, LPA2 and LPA3). More particularly the present invention is directed to LPA analogs wherein the glycerol is replaced with ethanolamine and a variety of substitutions have been linked at the second carbon atom.
