An active ingredient-containing dressing composition and method for manufacturing the same are provided. The active ingredient-containing dressing composition includes an electrospun fiber substrate and an active ingredient layer. The active ingredient layer is attached on a surface of the electrospun fiber substrate, and includes chitosan and at least one active ingredient.提供一種含活性成分的敷料組合物及其製造方法。此種含活性成分的敷料組合物包括電紡纖維基材以及活性材料層。活性材料層附著於電紡纖維基材的表面上,且包括幾丁聚醣及至少一種活性成分。S01、S02、S03‧‧‧步驟