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Mandelamide heterocyclic compounds
专利权人:
Yanlei Zhang;Robert J. Cherney
发明人:
Robert J. Cherney,Yanlei Zhang
申请号:
US13642755
公开号:
US08835470B2
申请日:
2011.04.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed are compounds of Formula (I) or stereoisomers, salts, or prodrugs thereof, wherein: Q is, or R1 is phenyl substituted with zero to 3 substituents; and R1, R2, R3, R4, R5, and G are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
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