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LIQUID PHARMACEUTICAL COMPOSITION
专利权人:
ARECOR LIMITED
发明人:
Luca BADIALI,David GERRING,Jan JEZEK
申请号:
US16491500
公开号:
US20200016074A1
申请日:
2018.03.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to novel liquid pharmaceutical compositions of adalimumab, which include adalimumab or a biosimilar thereof, EDTA, and a small polyol stabiliser such as glycerol. Such a combination of components furnishes formulations having a stability (e.g. on storage and when exposed to stress) which is comparable to or an improvement upon those known in the art, and with fewer ingredients. Such advances will help adalimumab treatments to become more widely available at lower cost, and prolong the viability of pre-loaded delivery devices (e.g. pre-filled syringes) to reduce unnecessary waste of the drug.
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