In vivo immunoimaging of interferon-gamma

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专利权人:

Wayne State University

发明人:

VIOLA-VILLEGAS, Nerissa,GIBSON, Heather

申请号：

AU2018321893

公开号：

AU2018321893A1

申请日:

2018.08.23

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

Methods for in vivo immunoimaging including: (a) administering a labeled-antibody conjugate to a subject, wherein the labeled-antibody conjugate includes: an antibody that specifically recognizes and binds to IFN-γ, and a detection label conjugated to the antibody, wherein the detection label is a radionuclide tracer or tluorophore； and (b) detecting the presence of the radiolabeled-antibody conjugate in the subject in vivo by imaging. Embodiments of the present disclosure are directed to labeled-antibody conjugates and therapeutic radionuclide- antibody conjugates.

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