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IN VIVO IMMUNOIMAGING OF INTERFERON-GAMMA
专利权人:
Wayne State University
发明人:
Nerissa Viola,Heather Gibson
申请号:
US16640456
公开号:
US20200206371A1
申请日:
2018.08.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Methods for in vivo immunoimaging including: (a) administering a labeled-antibody conjugate to a subject, wherein the labeled-antibody conjugate includes: an antibody that specifically recognizes and binds to IFN-γ, and a detection label conjugated to the antibody, wherein the detection label is a radionuclide tracer or fluorophore; and (b) detecting the presence of the radiolabeled-antibody conjugate in the subject in vivo by imaging. Embodiments of the present disclosure are directed to labeled-antibody conjugates and therapeutic radionuclide-antibody conjugates.
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