A compound of formula III: ** Formula ** an enantiomer, a diastereomer, a racemate, a crystalline form, a non-crystalline form, an amorphous form, a solvate, or a pharmaceutically acceptable salt thereof, in which: R1 is independently selects from the group consisting of: a carbocycle, heterocycle, aryl, heteroaryl, arylalkyl, heteroarylalkyl, arylalkenyl, heteroarylalkyl, arylalkyl, hetero-arylalkyl, arylaminocarbonyl, heteroarylaminocarbonyl, arylcarboxamido, heteroaryl-arboxy, heteroaryl, arboxy-aryloxycaridoamido arylalkoxy, heteroarylalkoxy, arylamino and heteroarylamino in which said carbocycle, heterocycle, aryl, arylalkyl, heteroaryl or heteroarylalkyl group may be substituted with 0-3 substituents R1a in which R1a is independently selected from the group consisting of: halogen, alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, alkylthioalkyl, hydroxyalkyl, mono, di or trihaloalkyl, mono, di or trihaloalkoxy, nitro, amino, mono or disubstituted amino, mono or disubstituted aminoalkyl, aminocarbonyl, mono or disubstituted aminocarbonyl, cyclic aminocarbonyl, aminosulfonyl, mono or disubstituted aminocarbonyl, alkylcarbonyl, cyclic alkylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl, arylcarbonyl cyclic alkylsulfonyl, arylsulfonyl, heteroarylsulfonyl, carboxylic acid, carboxylic acid esterified, alkylcarbonylamino, cyclic alkylcarbonylamino, aryl-carbonylamino, heteroarylcarbonylamino, cyano, arylalkyl, heteroarylalkyl, aryloxyalkyl, heteroaryloxyalkyl, arylthioalkyl, heteroarylthioalkyl, carbamate, carbamate mono or disubstituted, R1b-aryl and R1b-heteroaryl in which R1b is H, halogen, OH, amino, mono or disubstituted amino, mono, di or trihaloalkyl, alkoxy, mono, di or trihaloalkoxy, hydroxyalkyl, alkoxyalkyl, aminoalkyl, mono or disubstituted aminoalkyl, carboxamide, sulfonamide, carbamate, urea or cyano； R2 is independently selected from the group consisting of: H, amino, mono or disubst
