AVIR GREEN HILLS BIOTECHNOLOGY RESEARCH DEVELOPMENT TRADE AG
发明人:
CHRISTIAN KITTEL,NINA WRESSNIGG
申请号：
BRPI0821034
公开号：
BRPI0821034A2
申请日:
2008.12.22
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The present invention provides an influenza B virus M gene with a modification of at least one nucleotide proximate to the N-terminus of the M gene, more specifically at any one of nucleotide positions 265 to 294 of the M gene as well as an influenza B virus comprising said modified M gene. Further, its use for the preparation of a vaccine and methods for preparing said modified influenza virus are disclosed.
