Method of producing a temperature sensitive (ts) influenza virus

• 收藏
• 分享

专利权人:

发明人:

申请号：

EP12168901.2

公开号：

EP2497826A1

申请日:

2003.04.25

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Method of producing a temperature sensitive (ts) influenza virus, the method comprising:(a) introducing at least one mutation resulting in an amino acid substitution at a position selected from the group consisting of: PA431 PB2630 PA497 NP55 NP114 NP 410 NP 5 °9 M1159 and M1183 into an influenza B virus genome and (b) replicating the mutated influenza virus genome under conditions whereby virus is produced.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/