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Inhibitors of HCV NS3 serine protease
专利权人:
MEDIVIR AB
发明人:
ROSENQUIST, ASA,THORSTENSSON, FREDRIK,JOHANSSON, PER-OLA,KVARNSTROM, INGEMAR,SAMUELSSON, BERTIL,WALLBERG, HANS
申请号:
ES05704765
公开号:
ES2336009T8
申请日:
2005.01.28
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
Compounds of the formula where the variables are as defined in the specification inhibit the NS3 protease of flavivirus sych as hepatitis C virus (HCV). The compounds comprise a novel linkage between a heterocyclic P2 unit and those portions of the inhibitor more distal to the nominal cleavage site of the native substrate, which linkage reverses the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site.
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中国工程科技知识中心
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