HCV NS-3 SERINE PROTEASE INHIBITORS

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专利权人:

MEDIVIR AKTIEBOLAG

发明人:

ROSENQUIST, SA,THORSTENSSON, FREDRIK,JOHANSSON, PER-OLA,KVARNSTRM, INGEMAR,AYESA, SUSANA,CLASSON, BJRN,RAKOS, LAZLO,SAMUELSSON, BERTIL

申请号：

HK07108691.8

公开号：

HK1104044B

申请日:

2007.08.10

申请国别(地区):

HK

年份:

2014

代理人:

摘要：

Compounds of the formula where the variables are as defined in the specification inhibit the NS3 protease of flavivirus sych as hepatitis C virus (HCV). The compounds comprise a novel linkage between a heterocyclic P2 unit and those portions of the inhibitor more distal to the nominal cleavage site of the native substrate, which linkage reverses the orientation of peptidic bonds on the distal side relative to those proximal to the cleavage site.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/