PURPOSE: A composition containing a Chrysanthemum zawadskii extract is provided to suppress pancreatic beta cell damage and to prevent glucotoxicity. CONSTITUTION: A composition for preventing and treating diabetic disorders contains a Chrysanthemum zawadskii extract as an active ingredient. The extract is prepared using water or a low carbon number alcohol of C1-C4. The low carbon number alcohol is ethanol. The extract suppresses pancreatic beta cell damage to quickly recover damaged pancreatic beta cells. The extract also suppresses pancreatic beta cell apoptosis. The composition further contains a pharmaceutically acceptable carrier. The carrier is a diluent, a filler, a binder, a disintegrant, a disintegration inhibitor, an absorption promoting agent, a wetting agent, a lubricant, a suspension, a surfactant, or a flavoring agent. [Reference numerals] (AA) dRib(30mM)+Chrysanthemum zawadskii； (BB) Chrysanthemum zawadskii본 발명은 구절초 추출물을 포함하는 당뇨질환 예방 및 치료용 조성물에 관한 것이다. 본 발명에 따른 구절초 추출물을 포함하는 조성물은 췌장베타세포의 손상을 억제하고 손상된 췌장베타세포를 회복시켜, 인슐린 분비가 원활히 이루어지도록 하고 당독성을 방지하는 작용을 할 수 있다.
