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Aqueous-alcoholic, single-phase transcutaneous pharmaceutical compositions containing a steroid hormone
专利权人:
PIERRE FABRE MEDICAMENT
发明人:
LEVERD, ELIE,BOUGARET, JOEL
申请号:
NZ58675908
公开号:
NZ586759A
申请日:
2008.12.04
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
The disclosure relates to a transcutaneous pharmaceutical composition of monophasic hydroalcoholic type comprising: more than 30% of one or more short chain (C1-C4) alcohols, a steroidal hormone (such as testosterone), at least one fatty acid ester and propylene glycol as a penetration agent, wherein the concentration of said fatty acid ester and propylene glycol as penetration agent with a concentration of from 0.5% to 10% (m/m) of the composition, and an apolar solvent (such as N,N-di-ethyl-m-toluamide, commonly referred as DEET) soluble in the hydroalcoholic phase.
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