Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH);Max-Delbrück-Centrum für Molekulare Medizin (MDC)
发明人:
申请号:
EP18161391.0
公开号:
EP3369812A1
申请日:
2006.08.04
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCR's, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires.