The present disclosure illustrates an mite-removing vacuum cleaner including a cleaner body and a mite-removing device. The mite-removing device is detachably combined with a front section of the cleaner body and includes a circuit board, a vibrator and a UV sterilization lamp. The circuit board is electrically connected to a power source, and the vibrator is electrically connected to the circuit board. The UV sterilization lamp is located at the bottom surface of the mite-removing device and electrically connected to the circuit board. When the cleaner body is assembled with the mite-removing device, the mite-removing vacuum cleaner can perform mite-removing and dust-sucking functions both when the cleaner body is disassembled from the mite-removing device, the cleaner body can perform the dust-sucking function independently. Therefore, the mite-removing vacuum cleaner of the present disclosure can provide the mite-removing and dust-sucking functions both, or provide the dust-sucking function independently.