Carlos Martin Montanes,Brigitte Gicquel,Esther Perez Herran,Jesus Gonzalo Asensio,Ainhoa Arbues Arribas
申请号：
US13619615
公开号：
US08642011B2
申请日:
2012.09.14
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to an isolated microorganism belonging to the genus Mycobacterium, characterized in that it comprises inactivating the gene Rv0757 that confers a PhoP− phenotype and inactivating a second gene that prevents the production of DIM (DIM-phenotype). Additionally, the present invention comprises the use of said microorganism for producing a vaccine for immunizing against or preventing tuberculosis.
