Rama Rao Amara;Thomas M. Shinnick;Manl Cheruvu;Suraj Sable;Bonnie B. Plikaytis
发明人:
Suraj Sable,Bonnie B. Plikaytis,Thomas M. Shinnick,Rama Rao Amara,Manl Cheruvu
申请号:
US12812541
公开号:
US08741313B2
申请日:
2009.01.12
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A vaccine is provided wherein a polypeptide or combination of peptides from M. tuberculosis is administered to a subject to elicit an immune response. The polypeptide vaccine is administered as part of a prime-boost strategy with BCG vaccine to increase the immunoprotection in a subject such that prevention or elimination of disease is achieved. Finally, a pharmaceutical package is provided that encompasses a polypeptide vaccine for M. tuberculosis that when administered to a subject elicits immunoprotection.