BRIGITTE GICQUEL,CARLOS MARTIN MONTANES,ESTHER PEREZ HERRAN,JESUS GONZALO ASENSIO,AINHOA ARBUES ARRIBAS
申请号：
PT07730491
公开号：
PT1997881E
申请日:
2007.03.14
申请国别(地区):
PT
年份:
2013
代理人:
摘要：
The present invention relates to an isolated microorganism belonging to the Mycobacterium genus, characterised in that it comprises the inactivation of the Rv0757 gene that confers a PhoP- phenotype and the inactivation of a second gene that prevents DIM production (DIM- phenotype). Additionally, the present invention comprises the use of said microorganism for the preparation of a vaccine for the immunisation or prevention of tuberculosis.
