International Business Machines Corporation;Agency For Science, Technology and Research
发明人:
Daniel J. Coady,Richard A. Dipietro,Amanda C. Engler,James L. Hedrick,Victor M. L. Ng,Zhan-Yuin Ong,Jeremy P.K. Tan,Yi Yan Yang
申请号：
US15154948
公开号：
US20160257782A1
申请日:
2016.05.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Antimicrobial cationic polymers having one or two cationic polycarbonate chains were prepared by organocatalyzed ring opening polymerization. One antimicrobial cationic polymer has a polymer chain consisting essentially of cationic carbonate repeat units linked to one or two end groups. The end groups can comprise a covalently bound form of biologically active compound such as cholesterol. Other antimicrobial cationic polymers have a random copolycarbonate chain comprising a minor mole fraction of hydrophobic repeat units bearing a covalently bound form of a vitamin E and/or vitamin D2. The cationic polymers exhibit high activity and selectivity against Gram-negative and Gram-positive microbes and fungi.
