Juan Ignacio Jorquera Nieto;Pere Ristol Debart;Montserrat Costa Rierola
发明人:
Juan Ignacio Jorquera Nieto,Pere Ristol Debart,Montserrat Costa Rierola
申请号：
US13027447
公开号：
US08231599B2
申请日:
2011.02.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A process for detoxifying the blood of a patient in need thereof involves: collecting albumin from human plasma and/or plasma fractions； diafiltration of a mixture containing the collected albumin； stabilizing the resulting diafiltered albumin mixture with sodium chloride and an amino acid in the absence of any added fatty acid； pasteurizing the stabilized albumin mixture； diafiltering the pasteurized mixture to remove, among other things, stabilizers； and detoxifying the blood of the patient by administering the resulting albumin to the patient. In one embodiment, the amino acid stabilizing agent is acetyl tryptophan. The resulting albumin has at least about 80% albumin binding capacity relative to natural plasma albumin, and is storage stable for about 30 months at 30° C.
