Juan Ignacio Jorquera Nieto;Pere Ristol Debart;Montserrat Costa Rierola
发明人:
Juan Ignacio Jorquera Nieto,Pere Ristol Debart,Montserrat Costa Rierola
申请号：
US12268590
公开号：
US08088416B2
申请日:
2008.11.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A process for purifying and collecting albumin from plasma and plasma fractions involves diafiltration of an albumin-containing plasma fraction； stabilizing the resulting albumin fraction with sodium chloride and an amino acid in the absence of any added fatty acid； pasteurizing the stabilized albumin fraction； and diafiltering the pasteurized fraction to remove, along other things, stabilizers. In one embodiment, the amino acid stabilizing agent is acetyl tryptophan. The resulting albumin has at least about 80% albumin binding capacity relative to natural plasma albumin, and is storage stable for about 30 months at 30° C.
