BRAVO GONZALEZ, Roberto Carlos,BUSER, Thomas,GOUTTE, Frédéric Jean-Claude,BASIT, Abdul,VARUM, Felipe,FREIRE, Ana
申请号：
ES13723033
公开号：
ES2761341T3
申请日:
2013.04.29
申请国别(地区):
ES
年份:
2020
代理人:
摘要：
Delayed release of a drug to the colon is achieved from a delayed release formulation comprising a core and a coating for the core. The core comprises a drug and the coating comprises an inner layer and an outer layer. The outer layer comprises a mixture of a first polymeric material which is susceptible to attack by colonic bacteria, and a second polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a third polymeric material which is soluble in intestinal fluid.
