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A DELAYED RELEASE DRUG FORMULATION
专利权人:
TILLOTTS PHARMA AG
发明人:
BRAVO GONZÁLEZ, ROBERTO CARLOS,BUSER, THOMAS,GOUTTE, FRÉDÉRIC JEAN-CLAUDE,BASIT, ABDUL, WASEH,VARUM, FELIPE, JOSÉ, OLIVERIA,FREIRE, ANA, CRISTINA
申请号:
SG11201406798W
公开号:
SG11201406798WA
申请日:
2013.04.29
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
Delayed release of a drug to the colon is achieved from a delayed release formulation comprising a core and a coating for the core. The core comprises a drug and the coating comprises an inner layer and an outer layer. The outer layer comprises a mixture of a first polymeric material which is susceptible to attack by colonic bacteria, and a second polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a third polymeric material which is soluble in intestinal fluid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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