BUSER, Thomas,Goutte, Frédéric Jean-Claude,Basit, Abdul Waseh,Freire, Ana Cristina,Varum, Felipe José Oliveira,Bravo Gonzàles, Roberto Carlos
申请号：
DK12166110
公开号：
DK2659881T3
申请日:
2012.04.30
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
Delayed release of a drug to the colon is achieved from a delayed release formulation comprising a core and a coating for the core. The core comprises a drug and the coating comprises an inner layer and an outer layer. The outer layer comprises a mixture of a first polymeric material which is susceptible to attack by colonic bacteria, and a second polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a third polymeric material which is soluble in intestinal fluid.
