PERKINELMER HEALTH SCIENCES, INC.;PERKINELMER CELLULAR TECHNOLOGIES GERMANY GMBH
发明人:
BEHROOZ, ALI,KASK, PEET
申请号：
CA2990155
公开号：
CA2990155A1
申请日:
2015.07.29
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Presented herein, in certain embodiments, are approaches for robust bone splitting and segmentation in the context of small animal imaging, for example, microCT imaging. In certain embodiments, a method for calculating and applying single and hybrid second-derivative splitting filters to gray-scale images and binary bone masks is described. These filters can accurately identify the split lines/planes of the bones even for low-resolution data, and hence accurately morphologically disconnect the individual bones. The split bones can then be used as seeds in region growing techniques such as marker-controlled watershed segmentation. With this approach, the bones can be segmented with much higher robustness and accuracy compared to prior art methods.
