Provided in the present application are a preamble sequence configuration method, user equipment, and access network equipment, enabling user equipment to have a random access to a communication network system and reducing the random access failure rate. The method in an embodiment of the present application comprises: access network equipment determines preamble sequence information, the preamble sequence information comprising a message used to indicate the number of preamble sequences; and the access network equipment sends to user equipment the preamble sequence information used for the user equipment to perform a random access operation.