A system for clinical decision support includes a database of previously-recorded waveform data from comparator-patients and a comparator module. The comparator module receives physiological waveform data for a patient and identifies a pattern in the patient's physiological waveform data, wherein the pattern accounts for a morphology and a rhythm of the patient's physiological waveform. The comparator module then compares the patient's physiological waveform data to the previously-recorded waveform data using a pattern recognition algorithm to detect the pattern in the previously-recorded waveform data to identify one or more matches. The comparator module further generates a result set based on the one or more matches.