Luo, Jinquan,McCarthy, Stephen,Raju, T. Shantha,Scallon, Bernard,Spinka-Doms, Tracy
申请号:
AU2010318542
公开号:
AU2010318542A1
申请日:
2010.10.25
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Antibody and other Fc-containing molecules with glycosylation variations in the Fc region show increased resistance to proteases, such as pepsin, plasmin, trypsin, chymotrypsin, a matrix metalloproteinase, a serine endopeptidase, and a cysteine protease. The Fc-containing molecules are useful in the treatment of various diseases and disorders.