Antibody Glycosylation Variants

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专利权人:

Jinquan Luo

发明人:

Jinquan Luo,Stephen McCarthy,T. Shantha Raju,Bernard Scallon,Tracy Spinka-Doms

申请号：

US13504803

公开号：

US20120276092A1

申请日:

2010.10.25

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Antibody and other Fc-containing molecules with glycosylation variations in the Fc region show increased resistance to proteases, such as pepsin, plasmin, trypsin, chymotrypsin, a matrix metalloproteinase, a serine endopeptidase, and a cysteine protease. The Fc-containing molecules are useful in the treatment of various diseases and disorders.

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