LUO, JINQUAN,MCCARTHY, STEPHEN,RAJU, T. SHANTHA,SCALLON, BERNARD,SPINKA-DOMS, TRACY
申请号:
CA2778809
公开号:
CA2778809C
申请日:
2010.10.25
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
Antibody and other Fc-containing molecules with glycosylation variations in the Fc region show increased resistance to proteases, such as pepsin, plasmin, trypsin, chymotrypsin, a matrix metalloproteinase, a serine endopeptidase, and a cysteine protease. The Fc-containing molecules are useful in the treatment of various diseases and disorders.