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Biosynthetic production of acyl amino acids
专利权人:
发明人:
申请号:
EP14182110.8
公开号:
EP2946764A1
申请日:
2014.08.25
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to a cell for producing acyl amino acids wherein the cell is genetically modified to comprise- at least a first genetic mutation that increases the expression relative to the wild type cell of an amino acid-N-acyl-transferase,- at least a second genetic mutation that increases the expression relative to the wild type cell of an acyl-CoA synthetase, and- at least a third genetic mutation that decreases the expression relative to the wild type cell of at least one enzyme selected from the group consisting of an enzyme of the glycine cleavage system, glycine hydroxymethyltransferase (GlyA) and threonine aldolase (ItaE).
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