Process and at that time where the melted emulsion which consists of (i) continual phase and the activity which is made to disperse is produced the process where continual phase HSH (low DE) has toreharosu and the carbohydrate which are not, through (ii) type or the orifice, pushes in the melted emulsion, cools process and (iii) extrusion ones which form extrusion ones, dries the granule and the process which is made granule condition, with in (iv) case, method in order to produce the delivery system of the granule condition which is included.(i)連続相及び分散させた活性からなる溶融エマルションを製造する工程、その際連続相はHSH(低DE)ではないトレハロース及び炭水化物を有し、(ii)型又はオリフィスを介して溶融エマルションを押し込み、押出物を形成する工程、(iii)押出物を冷却し、そして顆粒状にする工程、(iv)場合により、顆粒を乾燥する工程、を含む顆粒状のデリバリーシステムを製造するための方法。
