Timothy A. Bertram,Deepak Jain,Joydeep Basu,John W. Ludlow
申请号：
US16624523
公开号：
US20200216816A1
申请日:
2018.06.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are, inter alia, compositions and methods for using genetically modified bioactive renal cell populations to provide regenerative effects to a native kidney for the treatment of chronic kidney disease. In certain embodiments, the aim is to effectively provide a “universal donor” immune-privileged renal cell population where gene editing is used to generate a modified allogeneic renal cell population to be administered to patients without immunosuppression.
