Raghavan Rajagopalan,Richard B. Dorshow,William L. Neumann
申请号：
US13343231
公开号：
US20120100078A1
申请日:
2012.01.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to pyrazine derivatives such as those represented by Formulas I and II below.X1 to X4 of the compounds of Formulas I and II may be characterized as electron withdrawing groups. In contrast, Y1 to Y4 of the compounds of Formulas I and II may be characterized as electron donating groups. Pyrazine derivatives of the present invention may be utilized in assessing renal function. In particular, an effective amount of a pyrazine derivative of the invention may be administered into a body of a patient. The pyrazine derivative that is in the body may be exposed to visible and/or infrared light to cause spectral energy to emanate from the pyrazine derivative. This emanating spectral energy may be detected and utilized to determine renal function of the patient.
