BERTRAM, TIMOTHY A.,JAIN, DEEPAK,BASU, JOYDEEP,LUDLOW, JOHN W.
申请号：
CA3065790
公开号：
CA3065790A1
申请日:
2018.06.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are, inter alia, compositions and methods for usinggenetically modified bioactive renal cell populationsto provide regenerative effects to a native kidney for the treatment ofchronic kidney disease. In certain embodiments, the aim is toeffectively provide a "universal donor" immune-privileged renal cellpopulation where gene editing is used to generate a modifiedallogeneic renal cell population to be administered to patients withoutimmunosuppression.
