The present invention relates to food or a drink composition including fermented eastern prickly pear, and more specifically, to food or a drink composition for improving gastroesophageal reflux and skin diseases including fermented eastern prickly pea. The food or a drink composition including fermented eastern prickly pear according to one embodiment of the present invention is manufactured by a step of adding sweetening agents to eastern prickly pear, fermented eastern prickly pear, or crushed eastern prickly pear and a step of adding yeast or yeast mold to the eastern prickly pear, the fermented eastern prickly pear, or the crushed eastern prickly pear and fermenting the mixture.COPYRIGHT KIPO 2014본 발명은 천년초 발효물을 함유하는 역류성 식도염 또는 피부 질환의 개선용 식품 혹은 음료 조성물에 관한 것이다.