Allison L. Marlow,Eli M. Wallace,Jeongbeob Seo,Joseph P. Lyssikatos,Hong-Woon Yang,James Blake
申请号：
US12577312
公开号：
US08101639B2
申请日:
2009.10.12
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are compounds of the Formulas I and Vand pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8 and R9, W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
