Eli M. Wallace;James Blake;Jeongbeob Seo;Joseph P. Lyssikatos;Allison L. Marlow;Hong Woon Yang
发明人:
Allison L. Marlow,Eli M. Wallace,Jeongbeob Seo,Joseph P. Lyssikatos,Hong Woon Yang,James Blake
申请号：
US12186273
公开号：
US08211920B2
申请日:
2008.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are compounds of the Formula Vand pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8 and R9, and W are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, and inflammatory conditions in mammals. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases and inflammatory conditions in mammals and pharmaceutical compositions containing such compounds.
