WALLACE, ELI,SEO, JEONG-BOB,LYSSIKATOS, JOSEPH P.,MARLOW, ALLISON,YANG, HONG WOON,BLAKE, JIM
申请号:
TW101112592
公开号:
TW201238951A
申请日:
2004.11.19
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein Rl, R2, R7, R8 and R9, W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.