PROBLEM TO BE SOLVED: To provide a method for producing a solid preparation and a tablet which suppresses the reduction in content of loxoprofen (its salt) and acetaminophen and suppresses an unpleasant odor in a solid preparation containing loxoprofen (its salt) and acetaminophen.SOLUTION: There is provided a solid preparation which comprises the following components (A), (B), and (C). There is provided a method for producing a tablet which comprises a step of subjecting a drug-containing powder containing following components (A), (B) and (C) to tableting and molding to obtain a tablet: the component (A): one or more selected from the group consisting of loxoprofen and its salt, the component (B): acetaminophen and the component (C): one or more selected from the group consisting of an aluminum-based antacid (c1) substantially containing no magnesium atom in the molecule and an organic acid (c2) substantially containing no amino group in the molecule.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】ロキソプロフェン(塩)とアセトアミノフェンとを含有する固形製剤において、ロキソプロフェン(塩)の含有量の低下および不快な臭いが抑制された固形製剤および錠剤の製造方法の提供。【解決手段】本発明の固形製剤は、下記(A)成分、(B)成分および(C)成分を含有する。本発明の錠剤の製造方法は、下記(A)成分、(B)成分および(C)成分を含む薬物含有粉体を打錠成形して錠剤を得る工程を有する。 (A)成分:ロキソプロフェンおよびその塩からなる群より選ばれる1種以上 (B)成分:アセトアミノフェン (C)成分:分子中にマグネシウム原子を実質的に含まないアルミニウム系制酸剤(c1)および分子中にアミノ基を実質的に含まない有機酸(c2)からなる群より選ばれる1種以上【選択図】なし
