您的位置: 首页 > 农业专利 > 详情页

AMINO ACID DERIVATIVES FUNCTIONALIZED ON THE N-TERMINUS CAPABLE OF FORMING DRUG ENCAPSULATING MICROSPHERES AND USES THEREOF
专利权人:
Massachusetts Institute of Technology
发明人:
Langer, Robert S.,Dong, Yizhou,Love, Kevin Thomas,Anderson, Daniel Griffith,Chen, Delai,Chen, Yi,Vegas, Arturo Jose,Alabi, Akinleye,Zhang, Yunlong
申请号:
AU2020201387
公开号:
AU2020201387A1
申请日:
2020.02.26
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020201387A120200312.pdf#####ABSTRACT Described herein are compounds and compositions that are characterized by the Markush formulae (I), (II), (III), (IV), (V), and (VI) underneath, where at least one terminal amino group is further functionalized by bearing a group of type (i), (ii), or (iii). Such compounds are obtained by reacting a terminal or internal amino group with epoxides, acrylates, or aldehydes bearing lipophilic groups. The resulting amino acid, peptide, polypeptide-lipids (named "APPLs" in the application) are deemed useful as drug delivery systems including nucleotide delivery to cells. Formulae (i), (ii), and (iii). See Fig. 1.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充