DIHYDROPTERIDINONE DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF农业专利-农业学术服务平台

发明人:: TANG, PENG CHO,邓炳初,鄧炳初,ZHANG, NONG,张农,張農,ZHANG, BAOLEI,张宝磊,張寶磊,WANG, WEIMIN,王伟民,王偉民,ZHENG, HAO,郑浩,鄭浩,WU, LIN,武林,武林

摘要：: The present disclosure relates to dihydropteridinone derivatives, preparation processes and pharmaceutical compositions containing them. Specifically, the present disclosure relates to dihydropteridinone derivatives presented by formula (I), preparation processes thereof and the uses for treatment especially for Plk kinase inhibitors, in which each substitute group of general formula (I) is as defined in specification.本發明涉及二氫喋啶酮類衍生物、其製備方法及其在醫藥上的應用。具體而言,本發明涉及一種通式(I)所示的新的二氫喋啶酮類衍生物、其製備方法及含有該衍生物的藥物組合物以及其作為治療劑特別是作為Plk激酶抑制劑的用途,其中通式(I)的各取代基同說明書中的定義相同。