The invention relates to the uses of pogostone (patchoulenone) and its derivatives in the preparation of antibacterial drugs, healthcare food, food, cosmetics, disinfectors or daily chemical articles. The invention also provides a type of antibacterial drug, healthcare food, food, cosmetics, disinfector or daily chemical article. Pogostone has good inhibitory effects on pathogenic bacteria (such as Staphylococcus, etc) or conditional pathogenic bacteria and can be effectively used for treatment of bacterial infectious diseases. Meanwhile, pogostone can also be active against methicillin-resistant bacteria, and thus can be developed as an potential antibacterial agent for clinical therapy.
