A communication system has a host communication circuit and a client communication circuit, which are connected to each other by means of a single signal wire. The host communication circuit generates a voltage modulated signal on the signal wire based on a reference clock signal, which in each clock cycle has a first period with a significant voltage change based on a clock edge of the reference clock signal, and a second period with a basically constant voltage variation. The host communication circuit (HCC) further can demodulate a current modulated signal received via the signal wire from the client communication circuit. The client communication circuit is configured to detect the significant voltage change in order to generate respective sync pulses in a sync signal, which is used to generate a client clock signal. A current modulation is performed by the client communication circuit based on the data to be transmitted a predetermined settling time after one of the sync pulses until the respective follo
