BOYS, MARK LAURENCE,BURGESS, LAURENCE E.,EARY, C. TODD,GRONEBERG, ROBERT,HACHE, BRUNO P.,HARVEY, DARREN,HICKEN, ERIK JAMES,KRASER, CHRISTOPHER F.,LAIRD, ELLEN,MORENO, DAVID A.,MUNSON, MARK C.,REN, LI
申请号：
CA2851623
公开号：
CA2851623A1
申请日:
2012.10.09
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3, R4, R5, R6, X1 and X2 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
