COMPOSES D'AMINE CYCLIQUE SUBSTITUES EN 1-(3-AMINOPROPYL), PROCEDE DE PREPARATION ET COMPOSITIONS PHARMACEUTIQUES DE CES DERNIERS ET LEURS UTILISATIONS

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专利权人:

CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA

发明人:

LIU, HONG,WU, BEILI,ZHENG, YONGTANG,XIE, XIN,JIANG, HUALIANG,PENG, PANFENG,LUO, RONGHUA,LI, JING,LI, JIAN,ZHU, YA,CHEN, YING,ZHANG, HAONAN,YANG, LIUMENG,ZHOU, YU,CHEN, KAIXIAN

申请号：

CA2935494

公开号：

CA2935494A1

申请日:

2014.12.29

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Provided are 1-(3-aminopropyl) substituted cyclic amine compounds as represented by formula (I), pharmaceutically acceptable salts, enantiomers, diastereoisomers, racemates and mixtures thereof, and a method of synthesizing said 1-(3-aminopropyl) substituted cyclic amine compounds by using aromatic heterocyclic formaldehyde as raw material. Said compounds can be used as CCR 5 antagonist for the treatment of HIV infection.

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