GERLACH, KAI,PRIEPKE, HENNING,WIENEN, WOLFGANG,SCHULER-METZ, ANNETTE,DAHMANN, GEORG,NAR, HERBERT
申请号：
EP08718234.1
公开号：
EP2132193B1
申请日:
2008.03.26
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Substituted amide compounds (I) and their tautomers, enantiomers, diastereomers or salts, are new. Substituted amide compounds of formula (I) and their tautomers, enantiomers, diastereomers or salts, are new. D : a substituted bicyclic ring system； L-E-G-J : a C-C-C-C-group, which is optionally substituted by R 4>； and R 5>；； L 1>；, L 2>；C(O)； R 4>；e.g. H, 1-6C-alkyl, 2-6C-alkenyl or 2-6C-alkynyl； R 5>；e.g. H, 1-5C-alkyl or 2-5C-alkenyl； and M : e.g. phenyl or pyridyl ring. With provisos. Full Definitions are given in the DEFINITIONS (Full Definitions) Field. [Image] ACTIVITY : Anticoagulant； Antiinflammatory； Vasotropic； Thrombolytic； Antibacterial； Immunosuppressive； Respiratory-Gen； Antiulcer； Gastrointestinal-Gen； Cardiant； Cerebroprotective； Neuroprotective； Nootropic； Antiparkinsonian； Cytostatic； Antiarthritic； Antirheumatic； Vulnerary. MECHANISM OF ACTION : Thrombosis factor Xa inhibitor； Serine protease inhibitor.
